Human Interferon beta / IFN-beta / IFNB Protein 10704-HNAS from Sino Biological, Inc.

Product Specs
ItemHuman Interferon beta / IFN-beta / IFNB Protein
CompanySino Biological, Inc.
Price Supplier Page View Company Product Page
Catalog Number10704-HNAS
Conjugate/TagUnconjugated
Purity> 95 % as determined by SDS-PAGE
TypeRecombinant protein
Molecular WeightThe recombinant human IFNβ consists of 166 amino acids and predicts a molecular mass of 20 KDa. It migrates as an approximately 20-23 KDa band in SDS-PAGE under reducing conditions
SpeciesHuman
Molecule NameIFNB1
Source/Expression SystemCHO Stable Cells
NCBI Full Gene Nameinterferon beta 1
NCBI Gene AliasesIFB, IFF, IFN-beta, IFNB
ActivityMeasured in antiviral assays using WISH cells infected with vesicular stomatitis virus. The ED50 for this effect is typically 2-20 pg/mL
FormatLyophilized from sterile 10mM NaAC, 40mM Arg, 0.12mg/ml Met, 146mg/ml Sucrose, 0.1% PF-68, pH 4.5

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Sino Biological, Inc.

1400 Liberty Ridge Drive

Suite 101

Wayne, PA 19087

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: http://www.sinobiological.com/

(1) Prohibitin1 facilitates viral replication by impairing the RIG-I-like receptor signaling pathwayJournal of virologyOctober 31, 2023Zou J, Tian S, Zhu Y, Cheng Y, Jiang M, Tu S, Jin M, Chen H, Zhou H.

(2) Enterovirus D68 infection upregulates SOCS3 expression to inhibit JAK-STAT3 signaling and antagonize the innate interferon response of the hostVirologica SinicaOctober 1, 2023Zhang Y, Xu L, Zhang Z, Su X, Wang Z, Wang T.purchased from Sino Biological Inc, Beijing, with the following product numbers: recombinant IFN-β (10704-HNAS, SinoBiological, China). 2.3 RNA extraction and qRT-PCR Total RNA was extracted using TRIzol reagent

(3) The SARS-CoV-2 papain-like protease suppresses type I interferon responses by deubiquitinating STINGScience signalingMay 2, 2023Cao D, Duan L, Huang B, Xiong Y, Zhang G, Huang H.

(4) Allelic imbalance of HLA-B expression in human lung cells infected with coronavirus and other respiratory virusesEuropean journal of human genetics : EJHGAugust 1, 2022Zhang Y, Sun Y, Zhu H, Hong H, Jiang J, Yao P, Liao H, Zhang Y.A549 cells were cultured in 6-well plates and treated with 1000 U/ml human recombinant IFNβ (Category No. 10704-HNAS, from Sino Biological Inc.) and harvested for RNA extraction at 4, 8 and 24 h. Total RNA was extracted

(5) Human Respiratory Syncytial Virus NS2 Protein Induces Autophagy by Modulating Beclin1 Protein Stabilization and ISGylationmBioFebruary 22, 2022Chiok K, Pokharel SM, Mohanty I, Miller LG, Gao SJ, Haas AL, Tran KC, Teng MN, Bose S.USA). Anti-ISG15 antibody was generated as described previously (46). Interferon beta (catalog no. 10704-HNAS) was purchased from Sino Biological US, Inc. (PA, USA). Cell culture and viruses. Cell cultures were

(6) Induced TRIM21 ISGylation by IFN-β enhances p62 ubiquitination to prevent its autophagosome targetingCell death & diseaseJuly 13, 2021Jin J, Meng X, Huo Y, Deng H.05-1308)(1:1000), Bafilomycin A1 (Selleck, S1413), IFNA2 (Sino Biological, 13833-HNAS), and IFN-β (Sino Biological, 10704-HNAS) were purchased from the corresponding manufactures. Short hairpin RNAs The short hairpin RNA (shRNA)

(7) The complex structure of GRL0617 and SARS-CoV-2 PLpro reveals a hot spot for antiviral drug discoveryNature communicationsJanuary 20, 2021Fu Z, Huang B, Tang J, Liu S, Liu M, Ye Y, Liu Z, Xiong Y, Zhu W, Cao D, et al.visualized using ChemiDoc system (Bio-Rad Laboratories, USA). In the assay of IFN-β (Sino Biological Inc., 10704-HNAS) induced ISGylation and the inhibition of PLpro by GRL0617, HEK293T cells were first treated with 500

(8) Acetylation-Dependent Deubiquitinase OTUD3 Controls MAVS Activation in Innate Antiviral ImmunityMolecular cellJuly 16, 2020Zhang Z, Fang X, Wu X, Ling L, Chu F, Li J, Wang S, Zang J, Zhang B, Ye S, et al.

(9) LYAR Suppresses Beta Interferon Induction by Targeting Phosphorylated Interferon Regulatory Factor 3Journal of virologyNovember 1, 2019Yang C, Liu X, Cheng T, Xiao R, Gao Q, Ming F, Jin M, Chen H, Zhou H.proteins used in this study were purchased from Sino Biological, Inc. (catalog numbers 12341-H08Y, 10704-HNAS, and 12339-H08H, respectively). Transfections. Transfections were performed using Lipofectamine 2000

(10) Influenza Virus NS1 Protein-RNA Interactome Reveals Intron TargetingJournal of virologyDecember 15, 2018Zhang L, Wang J, Muñoz-Moreno R, Kim M, Sakthivel R, Mo W, Shao D, Anantharaman A, García-Sastre A, Conrad NK, et al.indicated, ﬂavopiridol was added to the medium at 1 ␮M. HEK293T cells (ATCC) and IFN (catalog number 10704-HNAS; Sino Biological) were used for Fig. 8. Inﬂuenza virus A/WSN/33 (H1N1) strains were used. Inﬂuenza virus

(11) FAF1 Regulates Antiviral Immunity by Inhibiting MAVS but Is Antagonized by Phosphorylation upon Viral InfectionCell host & microbeDecember 12, 2018Dai T, Wu L, Wang S, Wang J, Xie F, Zhang Z, Fang X, Li J, Fang P, Li F, et al.

(12) Human Virus-Derived Small RNAs Can Confer Antiviral Immunity in MammalsImmunityJune 20, 2017Qiu Y, Xu Y, Zhang Y, Zhou H, Deng YQ, Li XF, Miao M, Zhang Q, Zhong B, Hu Y, et al.

(13) A Potent In Vivo Antitumor Efficacy of Novel Recombinant Type I InterferonClinical cancer research : an official journal of the American Association for Cancer ResearchApril 15, 2017Zhang KJ, Yin XF, Yang YQ, Li HL, Xu YN, Chen LY, Liu XJ, Yuan SJ, Fang XL, Xiao J, et al.

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Human Interferon beta / IFN-beta / IFNB Protein

Human Interferon beta / IFN-beta / IFNB Protein from Sino Biological, Inc.

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Sino Biological, Inc.

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Human Interferon beta / IFN-beta / IFNB Protein from Sino Biological, Inc.

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